MRT68921 (free base)

Name	MRT68921
Synonyms	MRT68921 MRT-68921 MRT 68921 MRT68921(HCI) MRT68921(HCl) MRT68921 (free base) N-[3-({5-Cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydro-6-isoquinolinyl)amino]-4-pyrimidinyl}amino)prop N-[3-({5-Cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydro-6-isoquinolinyl)amino]-4-pyrimidinyl}amino)propyl]cyclobutanecarboxamide Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-
CAS	1190379-70-4

Molecular Formula	C25H34N6O
Molar Mass	434.58
Solubility	10 mM in DMSO
Storage Condition	-20℃
In vitro study	MRT68921 disrupts Autophagosome Maturation by inhibiting ULK1-specific, thus blocking autophagy.

Last Update：2024-01-02 23:10:35

biological activity	MRT68921 is a potent dual autophagy kinase ULK1/2 inhibitor, its IC50 was 2.9 nM and 1.1 nM, respectively.
Target	Value
ULK2 (Cell-free assay)	1.1 nM
ULK1 (Cell-free assay)	2.9 nM

Last Update：2024-04-09 21:04:16

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CAS: 1190379-70-4
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Product Name: MRT68921 Visit Supplier Webpage Request for quotation
CAS: 1190379-70-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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MRT68921 (free base)

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